Homologous recombination-IN-1 是一种新型的RAD51-BRCA2蛋白-蛋白相互作用抑制剂 (EC50=19 μM)，可干扰同源重组。
| 生物活性 | Homologous recombination-IN-1 is a novelRAD51-BRCA2 protein-protein interactioninhibitor (EC50=19 μM). Homologous recombination-IN-1 can interfere with homologous recombination[1]. |
体外研究
(In Vitro) | Homologous recombination-IN-1 (10-40 μM; 5 h) reduces cell homologous recombination in a dose-dependent manner[1].
Western Blot Analysis[1] | Cell Line: | BxPC3 cells | | Concentration: | 10-40 μM | | Incubation Time: | 5 hours | | Result: | Led to homologous recombination inhibition with an EC50value of 18.4 μM. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | | Powder | -20°C | 3 years | | 4°C | 2 years | | In solvent | -80°C | 6 months | | -20°C | 1 month |
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