GLP-1(9-36)amide

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GLP-1(9-36)amide

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

161748-29-4

GLP-1(9-36)amide 是胰高血糖素样肽-1 (7-36) amide 的主要代谢产物。GLP-1(9-36)amide 是一种人胰腺GLP-1受体的拮抗剂。

生物活性

GLP-1(9-36)amide is a major metabolite of glucagon-like peptide-1-(7-36) amide formed by the enzyme dipeptidyl peptidase-4 (DPP-4). GLP-1(9-36)amide acts as an antagonist to the human pancreaticGLP-1 receptor^[1]^[2].

体外研究
(In Vitro)

GLP-1(9-36)amide potently inhibits hepatic glucose production (HGP) and is a weak insulinotropic agent^[2].

分子量

3089.41

性状

Solid

Formula

C₁₄₀H₂₁₄N₃₆O₄₃

CAS 号

161748-29-4

Sequence

Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2

Sequence Shortening

EGTFTSDVSSYLEGQAAKEFIAWLVKGR-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据

In Vitro:

H₂O : ≥ 25 mg/mL(8.09 mM)

*"≥" means soluble, but saturation unknown.

配制储备液

浓度溶剂体积质量

1 mg

5 mg

10 mg

1 mM	0.3237 mL	1.6184 mL	3.2369 mL
5 mM	0.0647 mL	0.3237 mL	0.6474 mL
10 mM	---	---	---

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month (sealed storage, away from moisture)。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。