GPR84 antagonist 2 (compound 33) 是一种口服有效的，选择性的GPR84拮抗剂(IC50=8.95 nM)。GPR84 antagonist 2 在钙动员试验中显示出更强的效力，并在 GPR84 激活时抑制中性粒细胞和巨噬细胞的趋化性。GPR84 antagonist 2 具有研究溃疡性结肠炎的潜力。
| 生物活性 | GPR84antagonist 2 (compound 33) is a potent, selective, and orally activeGPR84antagonist (IC50=8.95 nM).GPR84antagonist 2 shows improved potency in the calcium mobilization assay and the ability to inhibit the chemotaxis of neutrophils and macrophages uponGPR84activation.GPR84antagonist 2 has the potential for the research of ulcerative colitis[1]. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
