奥美拉唑代谢物奥美拉唑硫化物 (Ufiprazole) 是奥美拉唑的代谢物,奥美拉唑是质子泵抑制剂。
Cas No. | 73590-85-9 |
别名 | 奥美拉唑硫醚,Ufiprazole |
Canonical SMILES | COC1=CC=C2C(N=C(SCC3=C(C)C(OC)=C(C)C=N3)N2)=C1 |
分子式 | C17H19N3O2S |
分子量 | 329.4 |
溶解度 | DMF: 30 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 30 mg/ml,Ethanol: 25 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Omeprazole sulfide is an intermediate used in the production of the gastric proton pump inhibitors, omeprazole and esomeprazole . As a degradation product, it is reported to be a direct-acting inhibitor of cytochrome P450 2C19 in pooled human liver microsomes (IC50 = 9.7 µM). |