[Ala17]-MCH TFA 是一种 MCH (HY-P1525A) 的类似物，是MCHR1 的配体 (Ki=0.16 nM) 选择性优于对 MCHR2的 (Ki=34 nM)。Eu3+螯合标记 [Ala17]-MCH 对 MCHR1(Kd=0.37 nM) 亲和性高，而对 MCHR2的亲和性低。
| 生物活性 | [Ala17]-MCH TFA, a MCH analogue (HY-P1525A), is a selective ligand forMCHR1(Ki=0.16 nM) over MCHR2(Ki=34 nM). [Eu3+chelate-labeled [Ala17]-MCH shows high affnity for MCHR1(Kd=0.37 nM) while has little demonstrable binding affnity for MCHR2[1]. |
| IC50& Target | Ki: 0.16 nM (MCHR1)Ki: 34 nM (MCHR2)[1] |
| 分子量 | |
| Formula | |
| Sequence Shortening | DFDMLRCMLGRVYRPCAQV (Disulfide bridge:Cys7-Cys16) |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
