Ac-hMCH(6-16)-NH2 是人脑中MCH的非选择性肽类激动剂,其对MCH-1R 和MCH-2R 的IC50值分别为 0.16 nM 和2.7 nM。
生物活性 | Ac-hMCH(6-16)-NH2 binds to and activates equally well both humanMCH receptorspresent in the brain (non-selective agonist), withIC50values of 0.16 nM and 2.7 nM for MCH-1R and MCH-2R[1]. |
体外研究 (In Vitro) | Ac-hMCH(6-16)-NH2 exhibits EC50values of 20 nM and 98 nM for MCH-1R and MCH-2R in aequorin functional assay, respectively[1].
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Formula | |
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Sequence | Ac-Arg-Cys-Met-Leu-Gly-Arg-Val-Tyr-Arg-Pro-Cys-NH2 |
Sequence Shortening | |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |