Modipafant

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Modipafant

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:	122957-06-6
包装:	5mg
市场价:	17800元

UK-80067

Modipafant (UK-80067)，UK-74505 的对映体，是一种高效、具有口服活性的选择性的血小板活化因子(PAF)拮抗剂。Modipafant 展示了大约两倍于 UK-74505 的内在效力。

生物活性

Modipafant (UK-80067), the (+)-enantiomer of UK-74505, is a potent, orally active, and selective platelet-activating factor(PAF)antagonist. Modipafant exhibits approximately double the intrinsic potency of UK-74505^[1]^[2].

体外研究
(In Vitro)

when preincubated with rabbit platelets, the potency of antagonizing PAF induced aggregation increased markedly when preincubation time with Modipafant was increased from 2 min (IC₅₀=5.6 nM) to 60 min (IC₅₀=0.34 nM)^[2].

Clinical Trial

分子量

605.09

Formula

C₃₄H₂₉ClN₆O₃

CAS 号

122957-06-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.