UAMC-3203hydrochloride是有效,选择性的Ferroptosis抑制剂,IC50为12nM。
Cas No. | 2271358-65-5 |
Canonical SMILES | O=S(C(C=C1NCC2=CC=CC=C2)=CC=C1NC3CCCCC3)(NCCN4CCNCC4)=O.Cl |
分子式 | C25H38ClN5O2S |
分子量 | 508.12 |
溶解度 | DMSO : 50 mg/mL (98.40 mM) |
储存条件 | 4°C, away from moisture and light |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM[1].
IC50: 12 nM (Ferroptosis)[1] [1]. Devisscher L, et al. Discovery of Novel, Drug-Like Ferroptosis Inhibitors with in Vivo Efficacy. J Med Chem. 2018 Nov 21;61(22):10126-10140. |