IACS-8968是IDO和TDO的双抑制剂，其pIC50s值分别为6.43，<5。
| Cas No. | 2144425-14-7 |
| Canonical SMILES | O=C(N1)NC2(C(C)(C)CN(C3=CC(C(F)(F)F)=CC4=CN=CN34)CC2)C1=O |
| 分子式 | C17H18F3N5O2 |
| 分子量 | 381.35 |
| 溶解度 | DMSO : 50 mg/mL (131.11 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | IACS-8968 is a dual IDO and TDO inhibitor, with pIC50s of 6.43 for IDO and<5 for TDO, respectively.
pIC50: 6.43 (IDO),<5 (TDO)[1]. [1]. ARYL SULFONOHYDRAZIDES. WO 2017189386 A1 |
