KTX-955是一种有效的IRAK4降解剂,对 IRAK4 和 Ikaros 的DC50分别为 5 nM 和 130 nM。KTX-955 可用于抗癌研究。
生物活性 | KTX-955 is a potentIRAK4degrader withDC50values of 5 nM and 130 nM forIRAK4and Ikaros, respectively. KTX-955 can be used to research anticancer[1][2]. |
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体外研究 (In Vitro) | KTX-955 (compound I-312) degrades IRAK4 in OCI-LY10 at 24 hours with an IC50of<0.05 μM[1].
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |