MIF-IN-6 (compound 2d) 是一种有效的巨噬细胞迁移抑制因子 (MIF)抑制剂,IC50为 1.4 μM,Ki为 0.96 μM。MIF-IN-6 减弱 MIF 诱导的 ERK 磷酸化,抑制 A549 细胞增殖。
生物活性 | MIF-IN-6 (compound 2d) is a potentmacrophage migration inhibitory factor (MIF)inhibitor with anIC50of 1.4 μM and aKivalue of 0.96 μM, respectively. MIF-IN-6 attenuates MIF-inducedERKphosphorylation and inhibits proliferation of A549 cells[1]. |
IC50& Target | IC50: 1.4 μM (MIF)[1] Ki: 0.96 μM (MIF)[1] |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |