CHEMBL333994 (FK-480) 是一种有效的口服有效的胆囊收缩素 A (CCK-A) 拮抗剂，IC50 为 0.67 nM。
| Cas No. | 167820-10-2 |
| 别名 | FK-480 |
| Canonical SMILES | O=C(C(N1)=CC2=C1C=CC=C2)N[C@H]3C(N4C5=C(CC4)C=CC=C5C(C6=CC=CC=C6F)=N3)=O |
| 分子式 | C26H19FN4O2 |
| 分子量 | 438.45 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | CHEMBL333994 is a potent and orally effective Cholecystokinin A (CCK-A) antagonist, with an IC50 of 0.67 nM. [1]. Satoh Y, et al. Studies on a novel, potent and orally effective cholecystokinin A antagonist, FK-480. Synthesis and structure-activity relationships of FK-480 and related compounds. Chem Pharm Bull (Tokyo). 1994 Oct;42(10):2071-83. |
