Cenerimod (ACT-334441) 是一种有效、选择性和口服活性的 S1P1 受体调节剂，EC50 为 1 nM。
| Cas No. | 1262414-04-9 |
| 别名 | ACT-334441 |
| Canonical SMILES | OC[C@H](O)COC1=C(C)C=C(C2=NOC(C3=CC(C4CCCC4)=NC(OC)=C3)=N2)C=C1CC |
| 分子式 | C25H31N3O5 |
| 分子量 | 453.53 |
| 溶解度 | DMSO : ≥ 100 mg/mL (220.49 mM);Water :< 0.1 mg/mL (insoluble) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Cenerimod (ACT-334441) is a potent and orally available sphingosine 1-phosphate 1 receptor (S1P1) agonist extracted from patent WO 2016184939 A1 and WO 2011007324 A1, example 1, with an EC50 of 2.7 nM. References:
[1]. WO 2016184939 A1
[2]. WO 2011007324 A1 |
