BMS-813160 是一种有效的选择性 CCR2/5 双重拮抗剂。
| Cas No. | 1286279-29-5 |
| Canonical SMILES | CC(N[C@H]1[C@@H](N2C([C@@H](NC3=NC=NC4=CC(C(C)(C)C)=NN43)CC2)=O)CC[C@@H](NC(C)(C)C)C1)=O |
| 分子式 | C25H40N8O2 |
| 分子量 | 484.64 |
| 溶解度 | DMSO : 25 mg/mL (51.58 mM) |
| 储存条件 | 4°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | BMS-813160 is the first dual CCR2/CCR5 antagonist to enter clinical development for cardiovascular. References:
[1]. Norman P. et al. A dual CCR2/CCR5 chemokine antagonist, BMS-813160 Evaluation of WO2011046916. Expert Opin Ther Pat. 2011 Dec;21(12):1919-24. |
