Cas No. | 97781-16-3 |
别名 | 阿司匹林D4,Acetylsalicylic Acid-d4; ASA-d4 |
Canonical SMILES | OC(C1=C(OC(C)=O)C([2H])=C([2H])C([2H])=C1[2H])=O |
分子式 | C9H4D4O4 |
分子量 | 184.2 |
溶解度 | DMF: >30 mg/ml,DMSO: >41 mg/ml,Ethanol: >80 mg/ml,PBS (pH 7.2): >2.7 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Aspirin-d4 is intended for use as an internal standard for the quantification of aspirin by GC- or LC-MS. Aspirin is a non-selective, irreversible COX inhibitor. The IC50 values for ovine COX-1 and -2 are 0.75 and 1.25 mM, respectively. Aspirin acetylates COX-1 at Ser530 and COX-2 at Ser516 resulting in irreversible enzyme inhibition. |