首页 蛋白库 基因库 产品 会员服务
位置：首页 > 产品库 > D-erythro-Sphingosine hydrochloride
立即咨询
咨询类型：
     
*姓名：
*电话：
*单位：
Email：
*留言内容：
请详细说明您的需求。
*验证码：
 
D-erythro-Sphingosine hydrochloride
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
D-erythro-Sphingosine hydrochloride图片
CAS NO:2673-72-5

Erythrosphingosine hydrochloride
erythro-C18-Sphingosine hydrochloride
trans-4-Sphingenine hydrochloride
D-erythro-Sphingosine (Erythrosphingosine) hydrochloride 是一种特异性TRPM3活化剂。D-erythro-Sphingosine 还诱导视网膜母细胞瘤蛋白 (retinoblastoma protein) 去磷酸化。
生物活性

D-erythro-Sphingosine (Erythrosphingosine) hydrochloride is a specificTRPM3activator. D-erythro-Sphingosine also inducesretinoblastoma proteindephosphorylation[1][2].

IC50& Target[1][2]

TRPM3

 

Retinoblastoma protein

 

体外研究
(In Vitro)

Extracellular application of D-erythro-Sphingosine (20 μM) induces an increase in [Ca2+]iin TRPM3-transfected HEK293 cells within 20 to 30 s after start of application, whereas nontransfected control cells (NT) shows only very small responses[1].
D-erythro-Sphingosine (10 μM) induces currents through TRPM3[1].
Induction of retinoblastoma protein dephosphorylation by D-erythro-Sphingosine (500 nM; 24 h) precede inhibition of growth and a specific arrest in the G0/G1 phase of the cell cycle[2].

分子量

335.95

性状

Solid

Formula

C18H38ClNO2

CAS 号

2673-72-5

中文名称

D-赤式-鞘氨醇盐酸盐

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder-20°C3 years
4°C2 years
In solvent-80°C6 months
-20°C1 month
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2026