1-Deazaadenosine 是一种有效的腺苷脱氨酶 (ADA) 抑制剂，Ki值为 0.66 μM。 1-Deazaadenosine 在体外表现出抗癌活性，有潜力作为化疗试剂用于淋巴增生性疾病的研究。
| 生物活性 | 1-Deazaadenosine is a potentAdenosine deaminase(ADA)inhibitor with aKivalue of 0.66 μM. 1-Deazaadenosine exhibits anti-cancer activities in vitro and has the potential to be a chemotherapy agent for lymphoproliferative disorders[1][2]. |
体外研究
(In Vitro) | 1-Deazaadenosine shows good activity in vitro as inhibitor of HeLa, KB, P388, and L1210 leukemia cell line growth, with ID50values ranging from 0.34 μM (KB) to 1.8 μM (P388)[2].
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | | Powder | -20°C | 3 years | | 4°C | 2 years | | In solvent | -80°C | 6 months | | -20°C | 1 month |
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