UCK2 Inhibitor-2 是一种非竞争性尿苷胞苷激酶 2 (UCK2) 抑制剂,IC50值为 3.8 μM。UCK2 Inhibitor-2 可以抑制细胞中尿苷的回收。
生物活性 | UCK2 Inhibitor-2 is a non-competitiveuridine-cytidine kinase 2 (UCK2)inhibitor with anIC50value of 3.8 μM. UCK2 Inhibitor-2 can suppress uridine salvage in cells[1]. |
IC50& Target | |
体外研究 (In Vitro) | UCK2 Inhibitor-2 (compound 20874830) 在浓度为 50 μM 时对 K562 细胞中的尿苷补救有 52% 的抑制作用。DHODH 的抑制增加了尿苷的回收,而 UCK2 抑制剂 UCK2 Inhibitor-2 (compound 20874830) 可以抑制这种增加[1]。
|
分子量 | |
Formula | |
CAS 号 | |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |