首页 蛋白库 基因库 产品 会员服务
位置：首页 > 产品库 > Isoacteoside
立即咨询
咨询类型：
     
*姓名：
*电话：
*单位：
Email：
*留言内容：
请详细说明您的需求。
*验证码：
 
Isoacteoside
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Isoacteoside图片
CAS NO:61303-13-7
包装:20mg
市场价:1911元

Isoacteoside 是一种天然化合物，与作为阳性对照的氨基胍 (IC50=1,056 μM) 和槲皮素 (IC50=28.4 μM) 相比，对晚期糖基化终产物形成具有显着抑制作用，IC50 值为 4.6-25.7 μM。
Cas No.61303-13-7
别名异麦角甾苷; Isoverbascoside
化学名[(2R,3R,4S,5R,6R)-5-(3,4-dihydroxyphenyl)-6-ethoxy-3,5-dihydroxy-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]methyl (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
Canonical SMILESCCOC1C(C(C(C(O1)COC(=O)C=CC2=CC(=C(C=C2)O)O)O)OC3C(C(C(C(O3)C)O)O)O)(C4=CC(=C(C=C4)O)O)O
分子式C29H36O15
分子量624.59
溶解度≥ 62.5mg/mL in EtOH
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Isoacteoside is a natural compound which exhibit significant inhibition of advanced glycation end product formation with IC50 values of 4.6-25.7 μM, compared with those of aminoguanidine (IC50=1,056 μM) and quercetin (IC50=28.4 μM) as positive controls.IC50 value:Target:In the rat lens aldose reductase assay, acteoside, isoacteoside, and poliumoside exhibited greater inhibitory effects on rat lens aldose reductase with IC50 values of 0.83, 0.83, and 0.85 μM, respectively, than those of the positive controls, 3,3-tetramethyleneglutaric acid (IC50=4.03 μM) and quercetin (IC50=7.2 μM).

References:
[1]. Yu SY, et al. Caffeoylated phenylpropanoid glycosides from Brandisia hancei inhibit advanced glycation end product formation and aldose reductase in vitro and vessel dilation in larval zebrafish in vivo. Planta Med. 2013 Dec;79(18):1705-9.

 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024