Mycophenolic acid 是一种有效的非竞争性肌苷一磷酸脱氢酶 (IMPDH) 抑制剂，EC50 为 0.24 μM。
| Cas No. | 24280-93-1 |
| 别名 | 霉酚酸; Mycophenolate |
| 化学名 | (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoic acid |
| Canonical SMILES | CC1=C(C(=C(C2=C1COC2=O)O)CC=C(C)CCC(=O)O)OC |
| 分子式 | C17H20O6 |
| 分子量 | 320.34 |
| 溶解度 | ≥ 10.85mg/mL in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Mycophenolic acid (Mycophenolate) is an an immunosuppresant drug and has potent anti-proliferative activity. References:
[1]. Diamond, M.S., M. Zachariah, and E. Harris, Mycophenolic acid inhibits dengue virus infection by preventing replication of viral RNA. Virology, 2002. 304(2): p. 211-21.
[2]. Takhampunya, R., et al., Inhibition of dengue virus replication by mycophenolic acid and ribavirin. J Gen Virol, 2006. 87(Pt 7): p. 1947-52. |
