Antifungal agent 46 (compound 2f) 是一种有效的抗真菌剂。Antifungal agent 46 通过抑制蛋白质法尼基转移酶 (farnesyltransferase) 来抑制Ras信号。
| 生物活性 | Antifungal agent 46 (compound 2f) is a potent antifungal agent. Antifungal agent 46 preventsRassignaling by inhibiting proteinfarnesyltransferase[1]. |
体外研究
(In Vitro) | Antifungal agent 46 (compound 2f) inhibits growth at 12.5 μM in biofilm assay, corresponding to a 2-fold higher MIC thanAmphotericin B(HY-B0221)[1].
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体内研究
(In Vivo) | Antifungal agent 46 (compound 2f, 0.78 μM) inhibits FTase activityin vivo[1].
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
