MTP-IN-1是微粒体甘油三酯转移蛋白 (microsomal triglyceride transfer protein (MTP)) 抑制剂，IC50值为0.77±0.29 nM。
| 生物活性 | PF-02575799 is amicrosomal triglyceride transfer protein (MTP)inhibitor with anIC50of 0.77±0.29 nM. |
| IC50& Target | IC50: 0.77±0.29 nM (MTP)[1] |
体外研究
(In Vitro) | PF-02575799 is compound 13 from the reference[1].
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体内研究
(In Vivo) | PF-02575799 produces appreciable triglyceride effects at its minimally effective dose (10 mg/kg). PF-02575799 significant increase alanine transaminase at 100 mg/kg[1].
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
