Z-Pro-prolinal

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Z-Pro-prolinal

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

88795-32-8

N-Benzyloxycarbonyl-L-prolyl-L-prolinal

Z-Pro-prolinal (N-Benzyloxycarbonyl-L-prolyl-L-prolinal) 是一种特异的，具有口服活性的脯氨酰寡肽酶 (PREP) 抑制剂，对于猪 PREP 的IC₅₀为 0.4 nM。

生物活性

Z-Pro-prolinal (N-Benzyloxycarbonyl-L-prolyl-L-prolinal) is a specific, orally activeprolyl endopeptidase(PREP)inhibitor with anIC₅₀of 0.4 nM for porcine PREP^[1]^[2]^[3].

IC₅₀& Target

IC₅₀: 0.4 nM (porcine PREP)^[2]
K_i: 3.7 nM (PREP from bovine brain)^[1]

体内研究
(In Vivo)

Z-Pro-prolinal (N-Benzyloxycarbonyl-L-prolyl-L-prolinal) (100 mg/kg; p.o.; once) increases septal vasopressin content in rats^[3].

Animal Model:	Male Wistar rats^[3]
Dosage:	100 mg/kg
Administration:	Oral administration, once
Result:	Significantly increased the septal arginine-vasopressin (AVP) content.

分子量

330.38

Formula

C₁₈H₂₂N₂O₄

CAS 号

88795-32-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.