Peucedanocoumarin III 是一种 α-突触核蛋白(α-synuclein) 和亨廷顿蛋白聚集体抑制剂,增强了核和胞质 β23 聚集体的清除率,防止疾病相关蛋白(即突变亨廷顿蛋白和 α-突触核蛋白)诱导的细胞毒性。Peucedanocoumarin III 可用于帕金森疾病的研究。
生物活性 | Peucedanocoumarin III is an inhibitor of(alpha)-synucleinand Huntington protein aggregates that enhances the clearance of nuclear and cytoplasmic β23 aggregates and prevents cytotoxicity induced by disease-associated proteins (i.e., mutant Huntington proteins and α-synuclein). Peucedanocoumarin III may be used in Parkinson's disease research[1]. |
分子量 | |
Formula | |
CAS 号 | |
结构分类 | - Phenylpropanoids
- Coumarins
|
来源 | - Plants
- Umbelliferae
- Peucedanum japonicumThunb.
|
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |