1,3-Dicyclohexylurea (DCU) 是一种口服有效的sEH(可溶性环氧水解酶)抑制剂。口服 1,3-Dicyclohexylurea 纳米悬浮剂对高血压大鼠可增加暴露并降低血压。
| 生物活性 | 1,3-Dicyclohexylurea (DCU) is an orally active and potentsEH(soluble epoxide hydrolase) inhibitor. Oral Delivery of 1,3-Dicyclohexylurea nanosuspension enhances exposure and lowers blood pressure in hypertensive Rats[1]. |
体内研究
(In Vivo) | 1,3-Dicyclohexylurea (Sprague Dawley rats, 30 mg/kg, Orally, once) shows antihypertensive efficacy when milled to reduce particle size, thus improving dissolution and oral bioavailability[1].
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | | Powder | -20°C | 3 years | | 4°C | 2 years | | In solvent | -80°C | 6 months | | -20°C | 1 month |
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