ODN 1826 为 B 类 CpG ODN (寡脱氧核苷酸),是一种TLR9激动剂。ODN 1826 是一种在小鼠模型中诱导 NO 和 iNOS 产生的极好的免疫刺激剂。 CpG ODN 1826 增强细胞凋亡(apoptosis)。ODN 1826 序列:5’-tccatgacgttcctgacgtt-3’。
生物活性 | ODN 1826, a class B CpG ODN (oligodeoxynucleotide), is aTLR9agonist. CpG ODN 1826 is an excellent immunostimulator that induces NO andiNOSproduction in the murine model. CpG ODN 1826 enhances cellapoptosis. ODN 1826 sequence: 5’-tccatgacgttcctgacgtt-3’[1][2][3]. |
IC50& Target | |
性状 | |
CAS 号 | |
Sequence | DNA, d(P-thio)(T-C-C-A-T-G-A-C-G-T-T-C-C-T-G-A-C-G-T-T) |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | -20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |