Agatolimod sodium (ODN 7909) 是一种 B 类 CpG ODN,是一种< B >TLR9激动剂。Agatolimod sodium 可作为疫苗佐剂使用,可用于癌症的研究。序列: 5’-TCGTCGTTTTGTCGTTTTGTCGTT-3’。
生物活性 | Agatolimod sodium (ODN 7909) is a class B CpG ODN and is aTLR9agonist. Agatolimod sodium can be used as vaccine adjuvant. Agatolimod sodium can be used for the research ofcancer. Sequence: 5’-TCGTCGTTTTGTCGTTTTGTCGTT-3’[1][2]. |
IC50& Target[1] | |
体外研究 (In Vitro) | Agatolimod sodium (ODN 7909) (10 μg/mL; 24 and 48 h) 通过过表达 TLR9,增加辐射抗性人肺腺癌细胞株的辐射敏感性[1]。
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Sequence | DNA, d(P-thio)(T-C-G-T-C-G-T-T-T-T-G-T-C-G-T-T-T-T-G-T-C-G-T-T) |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |