CAS NO: | 40632-26-6 |
生物活性 | Cytarabine-d2 is the deuterium labeled Cytarabine. Cytarabine, a nucleoside analog, causes S phase cell cycle arrest and inhibitsDNA polymerase. Cytarabine inhibitsDNA synthesiswith anIC50of 16 nM. Cytarabine has antiviral effects againstHSV[1][2]. | ||||||||||||||||
体外研究 (In Vitro) | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. | ||||||||||||||||
分子量 | 245.23 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C9H11D2N3O5 | ||||||||||||||||
CAS 号 | 40632-26-6 | ||||||||||||||||
中文名称 | 阿糖胞苷 d2 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: H2O : ≥ 50 mg/mL(203.89 mM) *"≥" means soluble, but saturation unknown. 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |
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