10Z-Hymenialdisine ((Z)-Hymenialdisine) 是一种天然的生物活性吡咯生物碱。10Z-Hymenialdisine 是一种泛激酶抑制剂，具有抗癌活性。
| 生物活性 | 10Z-Hymenialdisine ((Z)-Hymenialdisine) is a natural bioactive pyrrole alkaloid. 10Z-Hymenialdisine is a pan kinase inhibitor, and has anticancer activities[1]. |
体外研究
(In Vitro) | 10Z-Hymenialdisine displays a moderate effect on (ARK5, VEGFR-2, SAK and PDGFR) protein kinases. 10Z-Hymenialdisine shows a potent inhibition of RAF/MEK-1/MAPK cascade with an IC50value of 6 nM[1].
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| 结构分类 | - Alkaloids
- Pyrrole Alkaloids
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| 来源 | marine sponge Axinella carteri |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | | Powder | -20°C | 3 years | | In solvent | -80°C | 6 months | | -20°C | 1 month |
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