Phleomycin 是在链霉菌中发现的，具有抗肿瘤活性的糖肽类抗生素 (antibiotic)，可引起 DNA 断裂。与博来霉素 (Bleomycin, HY-17565A) 类似，它与 DNA 结合并插入，破坏双螺旋结构的完整性。
| 生物活性 | Phleomycin is an anticancerglycopeptideantibioticfound inStreptomyces verticillus, which cause DNA cleavage. Phleomycin binds and intercalates DNA to damage the integrity of the double helix, which is similar to Bleomycin (HY-17565A)[1]. |
| IC50& Target | |
| 性状 | |
| CAS 号 | |
| 结构分类 | - Antibiotics
- Other Antibiotics
|
| 来源 | Streptoalloteichus hindustanus |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | -20°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen) |
| 溶解性数据 | In Vitro: H2O : 100 mg/mL(Need ultrasonic) |
