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Balhimycin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Balhimycin图片
CAS NO:140932-79-2

Balhimycin 是一种糖肽类抗生素,发现于 Amycolatopsis sp. 的发酵液,Balhimycin 具有对葡萄球菌和厌氧菌的抗菌活性。
生物活性

Balhimycin is aglycopeptideantibiotic, found from the fermentation broth of a Amycolatopsis sp. Balhimycin shows anti-bacterial activity against staphylococci and anaerobes[1].

IC50& Target

Glycopeptide

 

体外研究
(In Vitro)

Balhimycin (0.39-12.5 μg/mL; 18 h) shows bactericidal activity againstS. aureus,Streptococcusepidermidis, andstreptococcalstrains[1].
Balhimycin (0.39-12.5 μg/mL; 18 h) shows good bactericidal activity against differentStaphylococcalstrains[1].
Balhimycin (1-15 μg/mL; 30 min) leads to cell membrane scrambling of platelets, and shows stimulation of platelet apoptosis[2]

Cell Viability Assay[1]

Cell Line:Staphylococcus aureus209P,S. aureus3066,S. aureus20424,S. epidermidis178,S. epidermidis825,S. epidermidis823,S. haemolyticus712,S. haemolyticus809,StreptococcusATCC 29212,S. faecalisD 21777,S. faecalisD Endococcen,S. faeciumD-59,S. faeciumD-65
Concentration:0.39-12.5 μg/mL
Incubation Time:18 hours
Result:Showed MIC values ranging from 0.39 μg/mL to 12.5 μg/mL againstS. aureus,Streptococcusepidermidis, andstreptococcalstrains.

Cell Viability Assay[1]

Cell Line:Staphylococcus aureus3066,S. aureus20424,S. epidermidis825,S. haemolyticus712,Streptococcus faecalisATCC29212,S. faecalisD 21777,S. faecalisD-59
Concentration:0.39-1.56 μg/mL
Incubation Time:18 hours
Result:Showed MIC values ranging from 0.39 μg/mL to 1.56 μg/mL against staphylococcal strains.
分子量

1447.24

Formula

C66H73Cl2N9O24

CAS 号

140932-79-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

 
 
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