Ozenoxacin

立即咨询

Ozenoxacin

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

245765-41-7

奥泽沙星
T-3912

Ozenoxacin 是一种非氟喹诺酮抗菌剂，能够抵抗大多数从在皮肤和软组织感染中分离的微生物。

生物活性

Ozenoxacin is a nonfluorinatedquinoloneantibacterial, which shows potent activities against the mainmicroorganismsisolated from skin and soft tissue infections.

IC₅₀& Target

Quinolone

体外研究
(In Vitro)

Ozenoxacin (OZN) shows potent antibacterial activities against clinical isolates of Gram-positive microorganisms, with MICs ranging from 0.008 to 4 mg/L. Ozenoxacin shows good activities against strains of MRSA, MSSA, MSSE, and MRSE with 2, 3, or 4 mutations in the gyrA and grlA (parC) genes^[1]. Ozenoxacin inhibits MSSA strains and S. agalactiae strains, with the rates of resistance of >10^–10and 5.3 × 10^–10, respectively. The maximum MIC value for mutant strains is 8 mg/L for ozenoxacin^[2].

Clinical Trial

分子量

363.41

性状

Solid

Formula

C₂₁H₂₁N₃O₃

CAS 号

245765-41-7

中文名称

奥泽沙星

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

溶解性数据

In Vitro:

DMSO : 4.17 mg/mL(11.47 mM;ultrasonic and warming and heat to 70℃)

配制储备液

浓度溶剂体积质量

1 mg

5 mg

10 mg

1 mM	2.7517 mL	13.7586 mL	27.5171 mL
5 mM	0.5503 mL	2.7517 mL	5.5034 mL
10 mM	0.2752 mL	1.3759 mL	2.7517 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。