m-PEG6-CH2CH2CHO 是一种不可降解 (non-cleavable) 的 ADC linker，用于抗体偶联药物 (ADC) 的合成。m-PEG6-CH2CH2CHO 也是一种基于 PEG 的 PROTAC linker，可用于 PROTAC 的合成。
| Cas No. | 1058691-77-2 |
| 分子式 | C16H32O8 |
| 分子量 | 352.42 |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | m-PEG6-CH2CH2CHO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG6-CH2CH2CHO is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
