Kaurenoic acid 是一种来源 Sphagneticola trilobata 的二萜，能通过抑制细胞因子的产生和激活 NO-cyclic GMP-PKG-ATP- 敏感型钾通道信号通路来抑制炎症疼痛。
| Cas No. | 6730-83-2 |
| 别名 | 异贝壳杉烯酸；贝壳杉烯酸 |
| Canonical SMILES | C[C@@]1(C(O)=O)CCC[C@@]2(C)[C@@]3([H])[C@@]4(CC([C@H](CC3)C4)=C)CC[C@]12[H] |
| 分子式 | C20H30O2 |
| 分子量 | 302.45 |
| 溶解度 | DMF: 10 mg/ml,DMSO: 25 mg/ml,DMSO:PBS (pH 7.2) (1:2): 0.3 mg/ml,Ethanol: 10 mg/ml |
| 储存条件 | -20°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Kaurenoic acid is a diterpene from Sphagneticola trilobata, inhibits Inflammatory Pain by the inhibition of cytokine production and activation of the NO-cyclic GMP-PKG-ATP-sensitive potassium channel signaling pathway[1]. [1]. Mizokami SS, et al. Kaurenoic acid from Sphagneticola trilobata Inhibits Inflammatory Pain: effect on cytokine production and activation of the NO-cyclic GMP-protein kinase G-ATP-sensitive potassium channel signaling pathway. J Nat Prod. 2012 May 25;75(5):896-904. |
