Lp-PLA2-IN-1可以抑制beta-lactamase-IN-1的活性,例如动脉粥样硬化,阿尔茨海默氏症。
Cas No. | 1420367-28-7 |
Canonical SMILES | CN1C(N2CCC1)=CC(OCC3=CC(F)=C(OC4=CC=C(C(F)(F)F)N=C4)C(F)=C3)=NC2=O |
分子式 | C21H17F5N4O3 |
分子量 | 468.38 |
溶解度 | Ethanol : 25 mg/mL (53.38 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease. [1]. PCT Int. Appl. (2013), WO 2013014185 A1 20130131. |