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Artemisinin-d3
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Artemisinin-d3图片
CAS NO:176652-07-6

Qinghaosu-d3
NSC 369397-d3
Artemisinin-d3 (Qinghaosu-d3) 是 Artemisinin 的氘代物。Artemisinin (Qinghaosu) 是一种倍半萜烯内酯,从青蒿 (Artemisia annuaL.) 植物的地上部分分离的抗疟疾药物。Artemisinin 以剂量依赖性方式降低pAKT来抑制 AKT 信号通路。Artemisinin 可减少癌细胞的增殖,迁移,侵袭,肿瘤发生和转移,同时 Artemisinin 有神经保护作用。
生物活性

Artemisinin-d3 (Qinghaosu-d3) is the deuterium labeled Artemisinin. Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial drug isolated from the aerial parts of Artemisia annua L. plants[1]. Artemisinin inhibitsAKTsignaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reducescancercell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects[2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

285.35

Formula

C15H19D3O5

CAS 号

176652-07-6

中文名称

青蒿素 d3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

 
 
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