Grazoprevir sodium salt (MK-5172 sodium salt) 是选择性的丙型肝炎病毒 NS3/4a蛋白酶抑制剂，作用于 gt1b，gt1a，gt2a，gt2b 和 gt3a的Ki分别为 0.01 nM，0.01 nM，0.08 nM，0.15 nM 和 0.90 nM。Grazoprevir sodium salt 抑制 SARS-CoV-2 3CLpro活性。
| 生物活性 | Grazoprevir sodium salt (MK-5172 sodium salt) is a selective inhibitor ofHepatitis C virus NS3/4aprotease with broad activity across genotypes and resistant variants, withKis of 0.01 nM (gt1b), 0.01 nM (gt1a), 0.08 nM (gt2a), 0.15 nM (gt2b), 0.90 nM (gt3a), respectively[1][2]. Grazoprevir sodium salt inhibits SARS-CoV-2 3CLproactivity[3]. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
