Trimethoprim-D3 is the deuterium labeled Trimethoprim. Trimethoprim is a bacteriostaticantibioticand an orally activedihydrofolate reductaseinhibitor. Trimethoprim is active against a wide range ofGram-positiveandGram-negative aerobic bacteria. Trimethoprim has the potential for urinary tract infections, Shigellosis and Pneumocystis pneumonia treatment^[1][2][3].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

293.34

Solid

C₁₄H₁₅D₃N₄O₃

1189923-38-3

甲氧苄啶 D3

Room temperature in continental US; may vary elsewhere.