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Velagliflozin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Velagliflozin图片
CAS NO:946525-65-1

Velagliflozin是一种可口服的钠-葡萄糖协同转运蛋白2(SGLT2)抑制剂,具有抗糖尿病的活性。
Cas No.946525-65-1
Canonical SMILESO[C@H]1[C@H](C2=CC(CC3=CC=C(C4CC4)C=C3)=C(C#N)C=C2)O[C@H](CO)[C@@H](O)[C@@H]1O
分子式C23H25NO5
分子量395.45
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Velagliflozin is an orally available sodium-glucose cotransporter 2 (SGLT2) inhibitor, with anti-diabetic activity.

Velagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, with anti-diabetic activity[1].

Velagliflozin (1 mg/kg, p.o.) increases cholesterol, albumin, beta-hydroxybutyrate (BHB), nonesterified fatty acids (NEFA), and urinary glucose excretion, and decreases respiratory exchange ratio in cats[1].

[1]. Hoenig M, et al. Effects of the sodium-glucose cotransporter 2 (SGLT2) inhibitor velagliflozin, a new drug with therapeutic potential to treat diabetes in cats. J Vet Pharmacol Ther. 2018 Apr;41(2):266-273.

 
 
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