Astaxanthin，一种红色的膳食类胡萝卜素，可从雨生红球藻(Haematococcuspluvialis)等多种海洋生物中提取得到，是过氧化物酶体增殖物活化受体γ(PPARγ)的抑制剂，是具有抗增殖、神经保护作用和抗炎活性的有效抗氧化剂，可用于治疗多种疾病，如癌症和心血管疾病。因其鲜红的色泽，可用于动物饲料的着色剂。
| Cas No. | 472-61-7 |
| 别名 | 虾青素 |
| Canonical SMILES | CC(/C=C/C(C(C)(C[C@H](O)C1=O)C)=C1C)=C\C=C\C(C)=C\C=C\C=C(C)\C=C\C=C(C)\C=C\C(C(C)(C[C@H](O)C2=O)C)=C2C |
| 分子式 | C40H52O4 |
| 分子量 | 596.84 |
| 溶解度 | DMSO : 2 mg/mL (3.35 mM), Acetone :< 1 mg/mL (insoluble) |
| 储存条件 | -20°C, protect from light, stored under nitrogen,unstable in solution, ready to use. |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Astaxanthin, a red dietary carotenoid isolated from Haematococcus pluvialis, is an inhibitor of PPARγ and a potent antioxidant with antiproliferative, neuroprotective and anti-inflammatory activity[1]. Astaxanthin has potential in the treatment of various diseases, such as cancers and Parkinson's disease, cardiovascular disease[2]. Due to its bright red colour, Astaxanthin could be used as a food colorant in animal feeds[3]. [1]. Yang Y, et al. Epigenetic CpG Methylation of the Promoter and Reactivation of the Expression of GSTP1 by Astaxanthin in Human Prostate LNCaP Cells. AAPS J. 2017 Mar;19(2):421-430. [2]. Desheng Fu, et al. Effect of astaxanthin on retinal pigment epithelial cells in high glucose: an invitro study. Biomedical Research 2017; 28 (15): 6839-6843. [3]. Rachel K Johnston, et al. Effects of astaxanthin on Brachionus manjavacas (Rotifera) population growth. Aquaculture Research. 2018;49:2278-2287. |
