Tirandamycin A

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Tirandamycin A

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

34429-70-4

替达霉素A

Tirandamycin A, 一种抗生素，是一种细菌 RNA 聚合酶 (bacterial RNA polymerase) 抑制剂。Tirandamycin A 具有抗阿米巴原虫和抗菌性能。

生物活性

Tirandamycin A, anantibiotic, is abacterialRNA polymeraseinhibitor. Tirandamycin A has antiamoebic and antibacterial properties^[1]^[2].

IC₅₀& Target

Amebae

体外研究
(In Vitro)

A 60 μM treatment with Tirandamycin A results in a slightly stronger inhibition, demonstrating a 84.2% reduction in growth ofEntamoeba histolyticaHM-1:IMSS and 64.8% reduction in growth byEntamoeba histolyticaCol. Tirandamycin A inhibits chain initiation and elongation of bacterial RNA polymerase without acting on mammalian polymerases^[1].

分子量

417.45

Formula

C₂₂H₂₇NO₇

CAS 号

34429-70-4

中文名称

替达霉素A

结构分类

Antibiotics
Other Antibiotics

来源

Streptomyces flaveolus strain Tu 1240

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.