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Prostaglandin E3
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Prostaglandin E3图片
CAS NO:802-31-3
包装与价格：
包装价格(元)
50μg询价
100μg询价
500μg询价
1mg询价

Cas No.802-31-3
别名PGE3
化学名9-oxo-11α,15S-dihydroxy-prosta-5Z,13E,17Z-trien-1-oic acid
Canonical SMILESO=C1[C@H](C/C=C\CCCC(O)=O)[C@@H](/C=C/[C@@H](O)C/C=C\CC)[C@H](O)C1
分子式C20H30O5
分子量350.5
溶解度>100 mg/ml (from PGE2) in DMSO, >100 mg/ml (from PGE2) in DMF, >100 mg/ml (from PGE2) in Ethanol
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Prostaglandin E3 (PGE3) is formed via the cyclooxygenase (COX) metabolism of eicosapentaenoic acid. [1] In human ocular tissue, it comprises 2.4% of the COX products formed. [1] When applied to the eyes of a rabbit, a 1 &#181g dose of PGE3 decreases intraocular pressure from 21 mmHg to about 17 mmHg.[2]

Reference:
[1]. Kulkarni, P.S., and Srinivasan, B.D. Eicosapentaenoic acid metabolism in human and rabbit anterior uvea. Prostaglandins 31(6), 1159-1164 (1986).
[2]. Kulkarni, P.S., and Srinivasan, B.D. Prostaglandins E3 and D3 lower intraocular pressure. Investigative Ophthalmology & Visual Science 26, 1178-1182 (1985).

 
 
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