Remdesivir-D5 (GS-5734-D5) 是 Remdesivir 氘代物。Remdesivir (GS-5734) 是一种核苷类似物,具有抗病毒活性,在 HAE 细胞中,对SARS-CoV和MERS-CoV的EC50值为 74 nM,在延迟脑肿瘤细胞中,对鼠肝炎病毒的EC50值为 30 nM。Remdesivir 有潜力用于 2019-nCoV (COVID-19) 研究。
生物活性 | Remdesivir-D5 (GS-5734-D5) is a deuterium labeled Remdesivir. Remdesivir (GS-5734) is a nucleoside analogue, with effective antiviral activity, withEC50s of 74 nM forSARS-CoVandMERS-CoVin HAE cells, and 30 nM formurine hepatitis virusin delayed brain tumor cells. Remdesivir is highly effective in the control of 2019-nCoV (COVID-19)infectionin vitro[1][2]. |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Powder | -20°C | 3 years | | 4°C | 2 years | In solvent | -80°C | 6 months | | -20°C | 1 month |
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