DC41SMe 是一种 DC1 衍生物,对 Ramos、Namalwa 和 HL60/s 细胞显示细胞毒性,IC50值为 18-25 pM。DC1,CC-1065 的简化类似物,可用于靶向研究癌症的细胞毒性 DNA 烷基化酶的抗体偶联物。
生物活性 | DC41SMe, a DC1 derivative, shows cytotoxicity in Ramos, Namalwa, and HL60/s cells withIC50s ranging from 18-25 pM. DC1, a simplified analogue of CC-1065, is an antibody conjugate of cytotoxic DNA alkylators for the targeted treatment ofcancer[1][2]. |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |