DM3-SMe 是一种美登素衍生物，是一种微管蛋白 (tubulin) 抑制剂，是一种抗体偶联药物 (ADCs) 的细胞毒性部分，可通过二硫键或稳定的硫醚键与抗体连接。DM3-SMe 在体外显示出高度的细胞毒性活性，IC50为 0.0011 nM。
| 生物活性 | DM3-SMe is a maytansine derivative and atubulininhibitor, and is a cytotoxic moiety ofantibody-drug conjugates (ADCs), which can be linked to antibody through disulfide bond or stable thioether bond. DM3-SMe shows highly cytotoxic activity in vitro with anIC50of 0.0011 nM[1][2]. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
