Maytansinoid DM4 是一种具有强力细胞毒性的含硫醇美登素衍生物,可用作 ADC 毒性分子。
生物活性 | Maytansinoid DM4 is a thiol-containing maytansine derivative with highly potent cytotoxicity. Maytansinoid DM4 can be used as a cytotoxic moiety of ADC[1][2]. |
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体外研究 (In Vitro) | Maytansine is a natural benzoansamacrolide product isolated from the bark of the African shrubMaytenus ovatus. Maytansine binds to the same site on tubulin as the vinca alkaloids, with similar in vitro inhibition constants, but is a more-potent cytotoxin[1].
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |