MCC 是一种不可降解的 (non-cleavable) ADC 连接子,可用于合成 ADC,如 MCC-DM1。
生物活性 | MCC isnon-cleavableADC linker used in the synthesis ofantibody-drug conjugates (ADCs), such as MCC-DM1[1]. |
体外研究 (In Vitro) | Antibody-drug conjugates (ADCs) are potent cytotoxic drugs linked to antibodies through chemical linkers, and allow specific targeting of drugs to neoplastic cells. Anti-CD22-MCC-DM1 is broadly effective in vitro against multiple NHL cell lines[1].
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | -20°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen) |