NH2-MPAA-NODA is a nitroveratryl-based photocleavablelinker, it has a NODA motif and a methyl phenyl acetic acid (MPAA) backbone^[1]. NH2-MPAA-NODA can be used as a radiolabel by labeling with¹⁸F-fluoride.

IC50: Nitroveratryl-based photocleavable linker

NH2-MPAA-NODA contains the 1,4,7-triazacyclononane-1,4-diacetate (NODA) motif with a methyl phenyl acetic acid (MPAA) backbone, and it has enough ability to form stable Al18F-chelates. The organ of luoroaluminates are easily accessible from the reaction of 1 and AlF3.
NH2-MPAA-NODA can be conjugated to some inhibitors/antagonists labeled with¹⁸F for PET imaging of targeting tumors. It also can be used as a radiolabel of peptides^[1]

435.52

Solid

C₂₁H₃₃N₅O₅

Room temperature in continental US; may vary elsewhere.