Hydroxy-PEG3-(CH2)2-Boc

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

186020-66-6

Hydroxy-PEG2-(CH2)2-Boc 是一种用于合成抗体偶联药物 (ADC) 的ADC linker，Hydroxy-PEG2-(CH2)2-Boc 源于专利WO2004008101A2 (化合物 196)。Hydroxy-PEG2-(CH2)2-Boc 也可用作PROTAC linker用于 PROTAC 的合成。.

生物活性

Hydroxy-PEG2-(CH2)2-Boc is a uncleavableADC linkerused in the synthesis ofantibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196)^[1]. Hydroxy-PEG2-(CH2)2-Boc is also aPROTAClinkerthat can be used in the synthesis ofPROTACs.

IC₅₀& Target

Non-cleavable

PEGs

Alkyl/ether

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

分子量

278.34

性状

Liquid

Formula

C₁₃H₂₆O₆

CAS 号

186020-66-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)