Hydroxy-PEG2-(CH2)2-Boc 是一种用于合成抗体偶联药物 (ADC) 的ADC linker，Hydroxy-PEG2-(CH2)2-Boc 源于专利WO2004008101A2 (化合物 196)。Hydroxy-PEG2-(CH2)2-Boc 也可用作PROTAC linker用于 PROTAC 的合成。.
| 生物活性 | Hydroxy-PEG2-(CH2)2-Boc is a uncleavableADC linkerused in the synthesis ofantibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196)[1]. Hydroxy-PEG2-(CH2)2-Boc is also aPROTAClinkerthat can be used in the synthesis ofPROTACs. |
| IC50& Target | Non-cleavable | PEGs | Alkyl/ether |
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体外研究
(In Vitro) | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | | Pure form | -20°C | 3 years | | 4°C | 2 years | | In solvent | -80°C | 6 months | | -20°C | 1 month |
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